2-Chloro-6-methoxypyridine → HCID 9835756, compound

Participants

Reaction Steps

2-Chloro-6-methoxypyridine (305 mg, 2.1 mmol) was coupled to 3-tributylstannyl-7-trifluoromethylimidazo[1,2-α]pyrimidine (1.4 mmol) by the method of Example 1 to give 3-(6-methoxypyridin-2-yl)-7-trifluoromethylimidazo[1,2-α]pyrimidine (43 mg) as a white solid: δH (400 MHz, DMSO) 4.04 (3H, s), 6.84 (1H, d, J 8.2), 7.73 (2H, t, J 6.7), 7.88 (1H, t, J 7.8), 8.81 (1H, s), 10.37 (1H, d, J 7.0); m/z (ES+) 295 (M++H).

Provenance & Evidence