2-(2-Methyl-propane-1-sulfonylmethyl)-4-morpholin-4-yl-4-oxo-butyric acid → HCID 58619527, compound

HRID 1796164Notes

Reaction equation

HRID 1796164 reaction equation
[CH3:1][CH:2]([CH3:21])[CH2:3][S:4]([CH2:7][CH:8]([CH2:12][C:13]([N:15]1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1)=[O:14])[C:9]([OH:11])=O)(=[O:6])=[O:5].[NH2:22][CH:23]([CH2:37][CH3:38])[C@@H:24]([C:26]1[O:30][N:29]=[C:28]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[N:27]=1)[OH:25]>>[CH3:21][CH:2]([CH3:1])[CH2:3][S:4]([CH2:7][C@H:8]([CH2:12][C:13]([N:15]1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1)=[O:14])[C:9]([NH:22][C@H:23]([C:24]([C:26]1[O:30][N:29]=[C:28]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[N:27]=1)=[O:25])[CH2:37][CH3:38])=[O:11])(=[O:5])=[O:6]

Participants

3

Reactant 2

HCID 115659842-(2-Methyl-propane-1-sulfonylmethyl)-4-morpholin-4-yl-4-oxo-butyric acidHCID 68824651HCID 68824651, compound

Product 1

HCID 58619527HCID 58619527, compound

Procedure

It is similarly prepared according to general procedure given for Example 2 above but using 2-(2-Methyl-propane-1-sulfonylmethyl)-4-morpholin-4-yl-4-oxo-butyric acid and (S)-2-Amino-1-(3-phenyl-1,2,4-oxadiazol-5-yl)-butan-1-ol.

Workup

  1. customIt is similarly prepared

Sources & evidence

ORD record
ord-f690c75413b0482e9be028118d9605fd
Source dataset
uspto-grants-2006_04
Patent number
US07030116B2

Reaction notes

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