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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796179Generated: October 27, 2026

3-Benzylsulfonyl-2-(tetrahydro-pyran-4-yloxymethyl)-propionic acid → 3-Phenylmethanesulfonyl-n-[(s)-1-(5-phenyl-1,2,4-oxadiazole-3-carbonyl)-propyl]-2-(tetrahydro-pyran-4-yloxymethyl)-propionamide

https://huagongshe.com/reaction/1796179

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Benzylsulfonyl-2-(tetrahydro-pyran-4-yloxymethyl)-propionic acidHCID 22053974—
Reactant(S)-2-Amino-1-(5-phenyl-1,2,4-oxadiazol-3-yl)-butan-1-olHCID 67301524—
Product3-Phenylmethanesulfonyl-n-[(s)-1-(5-phenyl-1,2,4-oxadiazole-3-carbonyl)-propyl]-2-(tetrahydro-pyran-4-yloxymethyl)-propionamideHCID 10007870—

Reaction Steps

It is similarly prepared according to general procedure given for Example 1 above but using 2-Phenylmethanesulfonylmethyl-3-(tetrahydro-pyran-4-yloxy)-propionic acid and (S)-2-amino-1-(5-phenyl-1,2,4-oxadiazol-3-yl)-butan-1-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030116B2
Source datasetuspto-grants-2006_04
ORD IDord-6f5a3d9c61534720ae990c50ee53f5c8
Source noteuspto-grants-2006_04