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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796248Generated: November 1, 2026

HCID 68805308, compound → N-(4-Cyanophenyl)pyrrolidine-2-carboxamide

https://huagongshe.com/reaction/1796248

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68805308HCID 68805308—
SolventDichloromethaneHCID 6344—
SolventTrifluoroacetic acidHCID 6422—
ProductN-(4-Cyanophenyl)pyrrolidine-2-carboxamideHCID 12378874—

Reaction Steps

2-(4-Cyano-phenylcarbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester (3 g, 8 mmol) was dissolved in 90 mL of a 1:2 mixture of trifluoroacetic acid and dichloromethane. The reaction was stirred at ambient temperature for one hour then concentrated to yield title compound as an amber oil which was carried onto next step as is. APCI (AP−): 214.1 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030141B2
Source datasetuspto-grants-2006_04
ORD IDord-3d3021850d174d9da539c321f1a16189
Source noteuspto-grants-2006_04