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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 179636Generated: October 25, 2026

Dimethylformamide → 5-fluoro-4-[2-(1-hydroxycyclopentyl)ethynyl]-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-1H-indol-2-one

https://huagongshe.com/reaction/179636

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant1-EthynylcyclopentanolHCID 87074—
Reactant5-fluoro-4-iodo-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-1H-indol-2-oneHCID 53974358—
Product5-fluoro-4-[2-(1-hydroxycyclopentyl)ethynyl]-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-1H-indol-2-oneHCID 53875480—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-265e0887530c48e6912f04c3afb057f6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)