N,N-diethyl-4-{[2-(4-morpholinyl)ethyl]amino}-3-nitrobenzamide → 3-amino-N,N-diethyl-4-{[2-(4-morpholinyl)ethyl]amino}benzamide

Participants

Reaction Steps

A mixture of N,N-diethyl-4-{[2-(4-morpholinyl)ethyl]amino}-3-nitrobenzamide (1.10 g, 3.14 mmol) and 10% Pd/C in MeOH (50 mL) was hydrogenated for 2 hours at 40 psi. After the reaction was complete, the reaction mixture was filtered through diatomaceous earth. Removal of solvent provided the title compound (0.958 g, 95%) which was used without further purification. MS (ESI) (M+H)+=321.

Provenance & Evidence