HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-diethyl-3-nitro-4-[(2-phenylethyl)amino]benzamide → 3-amino-N,N-diethyl-4-[(2-phenylethyl)amino]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-diethyl-3-nitro-4-[(2-phenylethyl)amino]benzamide | HCID 22181379 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-amino-N,N-diethyl-4-[(2-phenylethyl)amino]benzamide | HCID 22181321 | 100.6% |
Reaction Steps
Following general procedure 2C: A mixture of N,N-diethyl-3-nitro-4[(2-phenylethyl)amino]benzamide (0.170 g, 0.498 mmol) and 10% Pd/C in EtOAc (10 mL) was hydrogenated at 40 psi. Usual work-up provided the title compound (0.156 g) which was used without further purification. MS (ESI) (M+H)+=312.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07030139B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-e0036e05688e4fbabc204e962e980402 |
| Source note | uspto-grants-2006_04 |