HCID 10297860, compound → HCID 10278790, compound

Participants

Reaction Steps

N-Cyclopentyl-4-[5,7-dichloro-2-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinamine (80 mg, 0.18 mmol) in cyclopentylamine was treated as described for Example 13 to give 70 mg (80%) of N-{4-[5-chloro-7-(cyclopentylamino)-2-(4-methoxyphenyl)pyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinyl}-N-cyclopentylamine as a solid. 1H NMR (CDCl3): δ 7.96 (d, 1H), 7.85 (s, 1H), 7.54 (d, 2H), 6.98 (d, 2H), 6.27 (d, 1H), 6.08 (d, 1H), 5.97 (d, 1H), 5.13 (d, 1h), 4.35 (m, 1H), 3.95 (m, 1H), 3.87 (s, 3H), 2.2–2.0 (m, 4H), 1.4–1.9 (m, 12H); MS m/z 503 (M+1).

Provenance & Evidence