反应详情

A mixture of 388B (1.20 g, 3.21 mmol), 10% Pd/C (360 mg) in MeOH (30 ml) was stirred vigorously under a balloon of H2 for 1.5 h, then filtered through celite and through 0.45μ syringe filter. The filtrate was concentrated to afford 388C (1.08 g, 98%) as a faintly reddish oil. LCMS Found: (M−tBu+2H)+=287.9.

1. filtrationfiltered through celite and through 0.45μ syringe
2. filtrationfilter
3. concentrationThe filtrate was concentrated