Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate → 1-amino-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester

HRID 1796650Notes

Reaction equation

HRID 1796650 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[NH:7][C:8]([CH3:17])=[C:9]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:10]=1[CH3:11])=[O:5])[CH3:2].C(OC(C1[N:24](N)C(C(OCC)=O)=CC=1)=O)C>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([NH2:24])[C:8]([CH3:17])=[C:9]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:10]=1[CH3:11])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 75526Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylateHCID 21025082diethyl 1-amino-1H-pyrrole-2,5-dicarboxylate

Product 1

HCID 210250851-amino-3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester

Procedure

Compound 409A was prepared from 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester by a route analogous to that used for the preparation of compound 406C.

Sources & evidence

ORD record
ord-42dab2b9a15648f19d1a263715914735
Source dataset
uspto-grants-2006_04
Patent number
US07030112B2

Reaction notes

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