Dimethylformamide → HCID 21025120, compound

Participants

Reaction Steps

Compound 429 (21 mg, 51%) was prepared from 4-chloro-3-cyano-5-methyl-pyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester (Example 1D) (26 mg, 0.1 mmol) and 429C (210 mg, 1.0 mmol) by a route analogous to that used for the preparation of compound 426, DMF (1 ml) was used as solvent instead of THF. 429 is a yellow solid and has a retention time of 6.24 min (standard LC1 method, 8 min run). MS Found: (M+H)+=414.2

Provenance & Evidence