Cyclohexylisopropylamine → HCID 22180481, compound

HRID 1796743Notes

Reaction equation

[C:1]1([CH:7]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][N:13]([C:16]3[C:17]([CH3:25])=[C:18]([CH:22]=[CH:23][CH:24]=3)[C:19](O)=[O:20])[CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:32]([NH:35][CH:36]1[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]1)([CH3:34])[CH3:33]>>[CH:36]1([N:35]([CH:32]([CH3:34])[CH3:33])[C:19](=[O:20])[C:18]2[CH:22]=[CH:23][CH:24]=[C:16]([N:13]3[CH2:12][CH2:11][N:10]([CH2:9][CH2:8][CH:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=4)[CH2:15][CH2:14]3)[C:17]=2[CH3:25])[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]1

Participants

Reactant 2

HCID 62386Cyclohexylisopropylamine

HCID 22180529HCID 22180529, compound

Product 1

HCID 22180481HCID 22180481, compound

Procedure

Step (d) of Example 1 was repeated, except that the compound prepared just above in step (c) was used instead of 3-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-2-methylbenzoic acid and N-isopropylcyclohexylamine was used instead of N-methylbenzylamine. Thus, the title compound was prepared.

Workup

customprepared just above in step (c)

Sources & evidence

ORD record: ord-05932c0c0bf74cbaad534fb6e5d16594
Source dataset: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07030120B2

Reaction notes

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