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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796747Generated: October 25, 2026

N-Allylcyclohexylamine → n-Allyl-n-cyclohexyl-5-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-2-isopropylbenzamide

https://huagongshe.com/reaction/1796747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-AllylcyclohexylamineHCID 81115—
Reactant2-Fluoro-5-nitrobenzoic acidHCID 280997—
Reactantn-Allyl-n-cyclohexyl-5-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-2-fluorobenzamideHCID 22180389—
Productn-Allyl-n-cyclohexyl-5-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-2-isopropylbenzamideHCID 22180348—

Reaction Steps

Steps (a) and (b) of Example 59 were repeated, except that the compound prepared just above in step (a) was used instead of 2-fluoro-5-nitrobenzoic acid. Step (d) of Example 1 was then repeated, except that N-allylcyclohexylamine was used instead of N-methylbenzylamine. Thus, the title compound was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030120B2
Source datasetuspto-grants-2006_04
ORD IDord-c81ce5498cca4b658ec1b00d9bacf2ba
Source noteuspto-grants-2006_04