Benzenemethanamine, N-cyclohexyl- → HCID 22180166, compound

HRID 1796751Notes

Reaction equation

HRID 1796751 reaction equation
[F:1][C:2]([F:42])([F:41])[CH2:3][NH:4][C:5]([C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:24]2[CH2:29][CH2:28][N:27]([C:30]3[CH:31]=[C:32]([CH:38]=[CH:39][CH:40]=3)[C:33]([O:35]CC)=O)[CH2:26][CH2:25]2)[C:19]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)=[O:6].[CH:43]1([NH:49][CH2:50][C:51]2[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=2)[CH2:48][CH2:47][CH2:46][CH2:45][CH2:44]1>>[CH2:50]([N:49]([CH:43]1[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48]1)[C:33](=[O:35])[C:32]1[CH:38]=[CH:39][CH:40]=[C:30]([N:27]2[CH2:28][CH2:29][N:24]([CH2:23][CH2:22][CH2:21][CH2:20][C:7]3([C:5](=[O:6])[NH:4][CH2:3][C:2]([F:42])([F:1])[F:41])[C:19]4[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=4[C:13]4[C:8]3=[CH:9][CH:10]=[CH:11][CH:12]=4)[CH2:25][CH2:26]2)[CH:31]=1)[C:51]1[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=1

Participants

3

Reactant 2

HCID 204463Benzenemethanamine, N-cyclohexyl-HCID 22180476HCID 22180476, compound

Product 1

HCID 22180166HCID 22180166, compound

Procedure

Steps (c) and (d) of Example 1 were repeated, except that the compound prepared in step (b) of Example 87 was used and N-cyclohexylbenzylamine was used instead of N-methylbenzylamine. Thus, the title compound was prepared.

Sources & evidence

ORD record
ord-9c2d5a7c856b4d79b7c385a8f907d470
Source dataset
uspto-grants-2006_04
Patent number
US07030120B2

Reaction notes

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