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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796759Generated: October 25, 2026

N-Allylcyclohexylamine → N-Allyl-N-cyclohexyl-2-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-5-methylisonicotinamide

https://huagongshe.com/reaction/1796759

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-AllylcyclohexylamineHCID 81115—
Reactant2-[4-(3,3-Diphenyl-1-propyl)piperazin-1-yl]-5-methylisonicotinic acidHCID 22180640—
ProductN-Allyl-N-cyclohexyl-2-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-5-methylisonicotinamideHCID 2218051172.8%

Reaction Steps

Step (d) of Example 107 was repeated, except that the compound (50 mg) prepared in step (d) of Example 108 and allylcyclohexylamine (34 mg) were used as the starting compounds. Thus, the title compound (47 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030120B2
Source datasetuspto-grants-2006_04
ORD IDord-8e757de0a427484089bebbeffbfb2f9f
Source noteuspto-grants-2006_04