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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796780Generated: November 2, 2026

Ethyl 4-(piperazin-1-yl)benzoate → ethyl 4-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]piperazin-1-yl]benzoate

https://huagongshe.com/reaction/1796780

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-(piperazin-1-yl)benzoateHCID 2761178—
Reactant4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromideHCID 22180203—
Productethyl 4-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]piperazin-1-yl]benzoateHCID 22180254—

Reaction Steps

Step (b) of Example 1 was repeated, except that the compound prepared in step (a) of Example 80 and the compound prepared in step (a) of Example 96 were used as the starting compounds. Thus, ethyl 4-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]-piperazin-1-yl]benzoate was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030120B2
Source datasetuspto-grants-2006_04
ORD IDord-50121c2dbe9342e5bf94cc6c07de4f69
Source noteuspto-grants-2006_04