Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Potassium bisulfate | HCID 516920 | — |
| Reactant | HCID 14014843 | HCID 14014843 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 13825239 | HCID 13825239 | — |
Reaction Steps
A solution of Example 3A (25.8 g, 100 mmol), sulfur trioxide pyridine complex (79.6 g, 500 mmol), and triethylamine (69.7 mL, 500 mmol) in DMSO (70 mL) at room temperature was stirred for 30 minutes, cooled to 0° C., treated with water and saturated aqueous KHSO4, and extracted with ethyl acetate. The extract was washed sequentially with saturated aqueous KHSO4 and brine, dried (MgSO4), filtered, and concentrated to provide the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07030262B2 |
|---|
| Source dataset | uspto-grants-2006_04 |
|---|
| ORD ID | ord-4830b46c0cb645de815e2941f2458363 |
|---|
| Source note | uspto-grants-2006_04 |
|---|
