1,3-Propanediol → 2-O-benzyl 3-O-methyl 6,10-dioxa-2-azaspiro[4.5]decane-2,3-dicarboxylate

HRID 179688Notes

Reaction equation

HRID 179688 reaction equation
[CH2:21]([CH2:22][CH2:23][OH:24])[OH:25].[CH3:26][CH:27]1[CH2:28][CH:29]([CH3:30])[O:31][C:32]2([CH2:33][N:34]([C:35](=[O:36])[CH:37]([CH:38]([CH3:39])[CH3:40])[NH:41][C:42]([O:43][CH3:44])=[O:45])[CH:46]([C:47]([O:48][CH3:49])=[O:50])[CH2:51]2)[O:52]1.[O:1]=[C:2]1[CH2:3][CH:4]([C:17](=[O:18])[O:19][CH3:20])[N:5]([C:7](=[O:8])[O:9][CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:6]1>>[O:1]1[C:2]2([CH2:3][CH:4]([C:17](=[O:18])[O:19][CH3:20])[N:5]([C:7](=[O:8])[O:9][CH2:10][c:11]3[cH:12][cH:13][cH:14][cH:15][cH:16]3)[CH2:6]2)[O:24][CH2:23][CH2:22][CH2:21]1

Participants

4

Reactant 3

HCID 104421,3-PropanediolHCID 133736081-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylateHCID 76757132Methyl 2-[2-(methoxycarbonylamino)-3-methylbutanoyl]-7,9-dimethyl-6,10-dioxa-2-azaspiro[4.5]decane-3-carboxylate

Product 1

HCID 767570732-O-benzyl 3-O-methyl 6,10-dioxa-2-azaspiro[4.5]decane-2,3-dicarboxylate

Sources & evidence

ORD record
ord-96091098fabc4fda8ef5e2a7e9fb329e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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