2-(Pyrrol-1-yl)thiobenzamide → 2-[2-(Piperidin-1-yl-o-tolylmethyl)-pyrrol-1-yl]-thiobenzamide

HRID 1796924Notes

Reaction equation

HRID 1796924 reaction equation
[N:1]1([C:6]2[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=2[C:8]([NH2:10])=[S:9])[CH:5]=[CH:4][CH:3]=[CH:2]1.[Cl-].[CH3:16][C:17]1[CH:29]=[CH:28][CH:27]=[CH:26][C:18]=1[CH:19]=[N+:20]1[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[N:20]1([CH:19]([C:18]2[CH:26]=[CH:27][CH:28]=[CH:29][C:17]=2[CH3:16])[C:5]2[N:1]([C:6]3[CH:14]=[CH:13][CH:12]=[CH:11][C:7]=3[C:8]([NH2:10])=[S:9])[CH:2]=[CH:3][CH:4]=2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

3

Reactant 2

HCID 27466962-(Pyrrol-1-yl)thiobenzamideHCID 179122571-(2-Methyl-benzylidene)-piperidinium chloride

Product 1

HCID 102219452-[2-(Piperidin-1-yl-o-tolylmethyl)-pyrrol-1-yl]-thiobenzamide

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 2-pyrrol-1-yl-thiobenzamide and 1-(2-methyl-benzylidene)-piperidinium chloride.

Sources & evidence

ORD record
ord-7709d36151c24530b0b4497b21977bf2
Source dataset
uspto-grants-2006_04
Patent number
US07034018B2

Reaction notes

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