HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 2-{2-[(2-Chloro-6-fluoro-phenyl)-pyrrolidin-1-yl-methyl]-pyrrol-1-ylmethyl}-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 2-Chloro-6-fluorobenzaldehyde | HCID 67847 | — |
| Reactant | 1-(2-Chloro-6-fluoro-benzylidene)-pyrrolidinium chloride | HCID 17912273 | — |
| Reactant | 4-Pyrrol-1-yl-methyl-pyridine | HCID 22174758 | — |
| Product | 2-{2-[(2-Chloro-6-fluoro-phenyl)-pyrrolidin-1-yl-methyl]-pyrrol-1-ylmethyl}-pyridine | HCID 10177159 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 4-pyrrol-1-yl-methyl-pyridine and 1-(2-chloro-6-fluoro-benzylidene)-pyrrolidinium chloride, which had been prepared in accordance with example 4 from 2-chloro-6-fluorobenzaldehyde and pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07034018B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-4ce91025180d4f7187cbbae89c5f61c7 |
| Source note | uspto-grants-2006_04 |