HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → 6-[2-(4-Methoxy-phenyl)-vinyl]-pyridine-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | 2-[2-(4-Methoxy-phenyl)-vinyl]-pyridine 1-oxide | HCID 69592112 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 6-[2-(4-Methoxy-phenyl)-vinyl]-pyridine-2-carbonitrile | HCID 69592023 | — |
Reaction Steps
Following the general method described in example 2b, 2-[2-(4-methoxy-phenyl)-vinyl]-pyridine 1-oxide was reacted first with dimethylsulfate and then with NaCN. After extraction and crystallization the title compound was obtained as a yellow crystalline material. Mp. 121–122° C. (isopropanol), MS: m/e=236 (M+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07034044B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-4823032ef01440d4b8de2bfb09759748 |
| Source note | uspto-grants-2006_04 |