Dimethyl Sulfate → HCID 69592128, compound

HRID 1797094Notes

Reaction equation

HRID 1797094 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N+:11]=1[O-].COS(OC)(=O)=O.[C-:24]#[N:25].[Na+]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]1[N:11]=[C:12]([C:24]#[N:25])[CH:13]=[CH:14][CH:15]=1

Participants

4

Reactant 3

HCID 6497Dimethyl SulfateHCID 8929Sodium CyanideHCID 69592105HCID 69592105, compound

Product 1

HCID 69592128HCID 69592128, compound

Procedure

Following the general method described in example 2b, 2-[2-(2-fluoro-phenyl)-vinyl]-pyridine 1-oxide was reacted first with dimethylsulfate and then with NaCN. After extraction and crystallization the title compound was obtained as a brown crystalline material. MS: m/e=224 (M+).

Workup

  1. extractionAfter extraction and crystallization the title compound
  2. customwas obtained as a brown crystalline material

Sources & evidence

ORD record
ord-671727e393cb4572a39e5a38fb52930d
Source dataset
uspto-grants-2006_04
Patent number
US07034044B2

Reaction notes

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