2-Methylpyridine 1-oxide → HCID 69592095, compound

HRID 1797095Notes

Reaction equation

HRID 1797095 reaction equation
[N+:1]1([O-:8])[C:2]([CH3:7])=[CH:3][CH:4]=[CH:5][CH:6]=1.C([O-])(C)(C)C.[K+].[F:15][C:16]([F:26])([F:25])[C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH:20]=O>>[F:15][C:16]([F:25])([F:26])[C:17]1[CH:18]=[C:19]([CH:20]=[CH:7][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N+:1]=2[O-:8])[CH:22]=[CH:23][CH:24]=1

Participants

4

Reactant 3

HCID 136022-Methylpyridine 1-oxideHCID 679903-(Trifluoromethyl)benzaldehydeHCID 23665647Potassium tert-butoxide

Product 1

HCID 69592095HCID 69592095, compound

Procedure

Following the general method described in example 2a, 2-picoline-1-oxide was reacted with potassium tert.-butanolate and 3-trifluoromethyl-benzaldehyde. After extraction and chromatography the title compound was obtained as a yellow solid material. MS: m/e=265 (M+).

Workup

  1. extractionAfter extraction and chromatography the title compound
  2. customwas obtained as a yellow solid material

Sources & evidence

ORD record
ord-89260a9ef3ca4805a76abeb88318a933
Source dataset
uspto-grants-2006_04
Patent number
US07034044B2

Reaction notes

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