2,2,2-Trifluoroethanesulfonyl chloride → HCID 22174503, compound

Participants

Reaction Steps

The reaction was conducted as described in the preparation of compound 179 using {4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl}(2-methylphenyl)methanone (0.15 g, 0.35 mmol)(disclosed in WO 01/05744) in pyridine (0.47 mL) and trifluoroethanesulfonyl chloride (0.059 mL, 0.53 mmol). The reaction time was 4 h. Work up as described in the preparation of compound 179 afforded the title compound as brown crystals.

Provenance & Evidence