Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 23567926 | HCID 23567926 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 9834575 | HCID 9834575 | — |
Reaction Steps
4.8 g (17.5 mmol) of 5-benzyloxy-2,2-dimethyl-3(S)-acetoxy-pentane-nitrile from the second fraction is dissolved in 50 ml of methanol and mixed with 1.4 g (35 mmol) of NaOH. It is stirred for 3 hours at 25° C., added to 200 ml of water, extracted with 2×200 ml of MTB ether, dried on sodium sulfate and concentrated by evaporation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07034165B2 |
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| Source dataset | uspto-grants-2006_04 |
|---|
| ORD ID | ord-39d289e167f2411e91d8403bc739c9f4 |
|---|
| Source note | uspto-grants-2006_04 |
|---|
