1-Butylpiperazine → HCID 57496138, compound

HRID 1797939Notes

Reaction equation

HRID 1797939 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:28])[NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18]([N:21]([CH2:25][CH2:26][OH:27])[CH2:22][CH2:23][OH:24])(=[O:20])=[O:19])=[CH:14][CH:13]=2)[CH:6]=[CH:7][CH:8]=1)#[N:2].[CH2:29]([N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1)[CH2:30][CH2:31][CH3:32]>>[CH2:29]([N:33]1[CH2:38][CH2:37][N:36]([C:1](=[NH:2])[C:3]2[CH:4]=[C:5]([NH:9][C:10](=[O:28])[NH:11][C:12]3[CH:13]=[CH:14][C:15]([S:18]([N:21]([CH2:22][CH2:23][OH:24])[CH2:25][CH2:26][OH:27])(=[O:19])=[O:20])=[CH:16][CH:17]=3)[CH:6]=[CH:7][CH:8]=2)[CH2:35][CH2:34]1)[CH2:30][CH2:31][CH3:32]

Participants

3

Reactant 2

HCID 4243221-ButylpiperazineHCID 57496177HCID 57496177, compound

Product 1

HCID 57496138HCID 57496138, compoundYield 18%

Procedure

The title compound was prepared from 4-(3-(3-cyanophenyl)ureido)-N,N-bis(2-hydroxyethyl)benzenesulfonamide following procedure C and using 2 equivalents of n-butylpiperazine as secondary amine. The product was purified by preparative HPLC.

Workup

  1. customThe product was purified by preparative HPLC

Sources & evidence

ORD record
ord-5e81d75ecf944940b7485ade204e9cf6
Source dataset
uspto-grants-2013_01
Patent number
US08343963B2

Reaction notes

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