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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1797941Generated: October 27, 2026

1-Butylpiperazine → 4-(3-(3-((4-butylpiperazin-1-yl)(imino)methyl)phenyl)ureido)-N-(7-chloroquinolin-4-yl)benzenesulfonamide

https://huagongshe.com/reaction/1797941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-ButylpiperazineHCID 424322—
ReactantN-(7-chloroquinolin-4-yl)-4-(3-(3-cyanophenyl)ureido)benzenesulfonamideHCID 57504195—
Product4-(3-(3-((4-butylpiperazin-1-yl)(imino)methyl)phenyl)ureido)-N-(7-chloroquinolin-4-yl)benzenesulfonamideHCID 4685213925%

Reaction Steps

The title compound was prepared from N-(7-chloroquinolin-4-yl)-4-(3-(3-cyanophenyl)ureido)benzenesulfonamide following procedure C and using 2.2 equivalents of n-butylpiperazine as secondary amine. The product was purified by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08343963B2
Source datasetuspto-grants-2013_01
ORD IDord-d8ccbdb214894d91b5fcf131790220c9
Source noteuspto-grants-2013_01