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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1797952Generated: November 2, 2026

4-Piperidinecarboxamide → 1-(imino(3-(3-(4-(N-(4-sulfamoylbenzyl)sulfamoyl)-phenyl)ureido)phenyl)methyl)piperidine-4-carboxamide

https://huagongshe.com/reaction/1797952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidinecarboxamideHCID 3772—
Reactant4-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamideHCID 57496180—
Product1-(imino(3-(3-(4-(N-(4-sulfamoylbenzyl)sulfamoyl)-phenyl)ureido)phenyl)methyl)piperidine-4-carboxamideHCID 5749614540%

Reaction Steps

The title compound was prepared from 4-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamide following procedure C and using 2.2 equivalents of piperidine-4-carboxamide as secondary amine. The product was purified by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08343963B2
Source datasetuspto-grants-2013_01
ORD IDord-8f36c4af8dac4d89a22654e05fbc3151
Source noteuspto-grants-2013_01