1-Butylpiperazine → HCID 57504035, compound

HRID 1797955Notes

Reaction equation

HRID 1797955 reaction equation
[CH2:1]([NH:8][S:9]([C:12]1[CH:17]=[CH:16][C:15]([NH:18][C:19]([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]#[N:29])[CH:23]=2)=[O:20])=[CH:14][CH:13]=1)(=[O:11])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:30]([N:34]1[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]1)[CH2:31][CH2:32][CH3:33]>>[CH2:1]([NH:8][S:9]([C:12]1[CH:13]=[CH:14][C:15]([NH:18][C:19]([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([C:28]([N:37]3[CH2:38][CH2:39][N:34]([CH2:30][CH2:31][CH2:32][CH3:33])[CH2:35][CH2:36]3)=[NH:29])[CH:23]=2)=[O:20])=[CH:16][CH:17]=1)(=[O:10])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 4243221-ButylpiperazineHCID 22318901HCID 22318901, compound

Product 1

HCID 57504035HCID 57504035, compoundYield 6%

Procedure

The title compound was prepared from N-benzyl-4-(3-(3-cyanophenyl)ureido)benzenesulfonamide following procedure C and using 3 equivalents of n-butylpiperazine as secondary amine. The product was purified by preparative HPLC.

Workup

  1. customThe product was purified by preparative HPLC

Sources & evidence

ORD record
ord-8cf8213758714ce09ea9f6e0be429030
Source dataset
uspto-grants-2013_01
Patent number
US08343963B2

Reaction notes

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