1-Butylpiperazine → HCID 46852143, Verbindung

HRID 1797961Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1797961
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:34])[NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18]([NH:21][CH:22]([C:24]3[CH:29]=[CH:28][C:27]([S:30](=[O:33])(=[O:32])[NH2:31])=[CH:26][CH:25]=3)[CH3:23])(=[O:20])=[O:19])=[CH:14][CH:13]=2)[CH:6]=[CH:7][CH:8]=1)#[N:2].[CH2:35]([N:39]1[CH2:44][CH2:43][NH:42][CH2:41][CH2:40]1)[CH2:36][CH2:37][CH3:38]>>[CH2:35]([N:39]1[CH2:44][CH2:43][N:42]([C:1](=[NH:2])[C:3]2[CH:4]=[C:5]([NH:9][C:10](=[O:34])[NH:11][C:12]3[CH:17]=[CH:16][C:15]([S:18]([NH:21][CH:22]([C:24]4[CH:29]=[CH:28][C:27]([S:30](=[O:32])(=[O:33])[NH2:31])=[CH:26][CH:25]=4)[CH3:23])(=[O:20])=[O:19])=[CH:14][CH:13]=3)[CH:6]=[CH:7][CH:8]=2)[CH2:41][CH2:40]1)[CH2:36][CH2:37][CH3:38]

Komponenten

3

Edukt 2

HCID 4243221-ButylpiperazineHCID 574961834-(3-(3-cyanophenyl)ureido)-N-(1-(4-sulfamoylphenyl)ethyl)benzenesulfonamide

Produkt 1

HCID 46852143HCID 46852143, VerbindungAusbeute 8 %

Versuchsvorschrift

The title compound was prepared from 4-(3-(3-cyanophenyl)ureido)-N-(1-(4-sulfamoylphenyl)ethyl)benzenesulfonamide following procedure C and using 2 equivalents of n-butylpiperazine as secondary amine. The product was purified by preparative HPLC.

Aufarbeitung

  1. customThe product was purified by preparative HPLC

Quellen und Nachweise

ORD-Eintrag
ord-52494ba9747345f58c9f43581d20fb1c
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08343963B2

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