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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1797978Generated: November 3, 2026

Propyl piperazine-1-carboxylate → propyl 4-(imino(3-(3-(4-(N-(4-sulfamoylbenzyl)sulfamoyl)phenyl)ureido)phenyl)methyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/1797978

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropyl piperazine-1-carboxylateHCID 22393735—
Reactant4-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamideHCID 57496180—
Productpropyl 4-(imino(3-(3-(4-(N-(4-sulfamoylbenzyl)sulfamoyl)phenyl)ureido)phenyl)methyl)piperazine-1-carboxylateHCID 57496164—

Reaction Steps

The title compound was prepared from 4-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamide following procedure C and using 1 equivalent of propyl piperazine-1-carboxylate. The product was purified by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08343963B2
Source datasetuspto-grants-2013_01
ORD IDord-5168a9be03e948b2ba2eb727d197ce09
Source noteuspto-grants-2013_01