HCID 58292872, compound → HCID 58292618, compound

Participants

Reaction Steps

To a solution of [6-(3-cyano-pyrazin-2-yloxy)-1-hydroxy-4-methyl-1,3-dihydro-benzo[c][1,2]oxaborol-3-yl]-acetic acid ethyl ester (200 mg, 0.566 mmol) in MeOH (10 mL) was added Pd/C (20 mg), HCl (conc., 2 drops). The resulting solution was degassed, and reacted under 1-atm H2 balloon for 6 hrs. The mixture was filtrated. The filtration was removed in vacuo to afford the title compound (190 mg, 94%) as a light yellow solid. MS found: (M+H)+=358.

Provenance & Evidence