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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1798363Erstellt: 25. Oktober 2026

Ammonia → 2-(4-Chloro-phenyl)-N-methyl-2-[4-(1H-pyrazol-4-yl)-phenyl]-acetamide

https://huagongshe.com/reaction/1798363

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktAmmoniaHCID 222—
EduktMethylamineHCID 6329—
EduktBis(4-chlorophenyl)acetic acidHCID 6730—
Edukt3-(4-Chloro-phenyl)-3-[4-(1H-pyrazol-4-yl)-phenyl]-propylamineHCID 11771347—
Produkt2-(4-Chloro-phenyl)-N-methyl-2-[4-(1H-pyrazol-4-yl)-phenyl]-acetamideHCID 11359296—

Reaktionsschritte

By following the procedure described in Example 12A followed by 12C but substituting 3-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-propionic acid for Bis-(4-chloro-phenyl)-acetic acid and ammonia for methyl amine, the title compound was obtained. LC/MS (PS-A2): Rt 2.64 [M+H]+ 326. 1H NMR (Me-d3-OD) 2.79 (3H, s), 4.94, (1H, br s), 7.26-7.35 (6H, m), 7.55-7.57 (2H, m), 7.96 (2H, br s)

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08343953B2
Quelldatensatzuspto-grants-2013_01
ORD IDord-091dc25479e04d8d83381ef42150ab86
Quellennotizuspto-grants-2013_01