1-Piperazinecarboxaldehyde → HCID 44137513, compound

HRID 1798497Notes

Reaction equation

C([NH:5][C:6]1[N:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[CH:9]=[C:8]([C:18]2[CH:19]=[N:20][CH:21]=[C:22]([C:24]3[CH:29]=[CH:28][C:27]([C:30]([N:32]4[CH2:37][CH2:36][N:35]([CH:38]([CH3:40])[CH3:39])[CH2:34][CH2:33]4)=[O:31])=[CH:26][CH:25]=3)[CH:23]=2)[CH:7]=1)(C)(C)C.N1(C=O)CCNCC1>>[NH2:5][C:6]1[N:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[CH:9]=[C:8]([C:18]2[CH:19]=[N:20][CH:21]=[C:22]([C:24]3[CH:25]=[CH:26][C:27]([C:30]([N:32]4[CH2:37][CH2:36][N:35]([CH:38]([CH3:40])[CH3:39])[CH2:34][CH2:33]4)=[O:31])=[CH:28][CH:29]=3)[CH:23]=2)[CH:7]=1

Participants

Reactant 2

HCID 821911-Piperazinecarboxaldehyde

HCID 68762778HCID 68762778, compound

Product 1

HCID 44137513HCID 44137513, compound

Procedure

This compound is prepared from [4-(6′-tert-Butylamino-[2,2′;4′,3″]terpyridin-5″-yl)-phenyl]-(4-isopropyl-piperazin-1-yl)-methanone (Example 2.73) analogously to 4-(6′-Amino-[2,2′;4′,3″]terpyridin-5″-yl)-phenyl]-piperazin-1-yl-methanone (Example 2.50).

Sources & evidence

ORD record: ord-9225a98a08c348b885fada4e36d19d5a
Source dataset: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08343966B2

Reaction notes

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