HCID 68734156, compound → HCID 68757887, compound

HRID 1798519Notes

Reaction equation

HRID 1798519 reaction equation
[CH2:1]([NH:8][C:9]1[N:14]=[C:13]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)[CH:12]=[C:11]([C:21]2[CH:22]=[N:23][CH:24]=[C:25]([C:27]#[C:28][CH2:29][N:30]3[CH2:35][CH2:34][N:33]([C:36]([CH3:39])([CH3:38])[CH3:37])[CH2:32][CH2:31]3)[CH:26]=2)[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:40](NC1N=C(C2C=CC=C(C)N=2)C=C(C2C=NC=C(Br)C=2)C=1)C1C=CC=CC=1>>[CH2:1]([NH:8][C:9]1[N:14]=[C:13]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([CH3:40])[N:16]=2)[CH:12]=[C:11]([C:21]2[CH:22]=[N:23][CH:24]=[C:25]([C:27]#[C:28][CH2:29][N:30]3[CH2:35][CH2:34][N:33]([C:36]([CH3:39])([CH3:38])[CH3:37])[CH2:32][CH2:31]3)[CH:26]=2)[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 68734156HCID 68734156, compoundHCID 68761698HCID 68761698, compound

Product 1

HCID 68757887HCID 68757887, compound

Procedure

This compound is prepared analogously to Benzyl-{5″-[3-(4-tert-butyl-piperazin-1-yl)-prop-1-ynyl]-[2,2′;4′,3″]terpyridin-6′-yl}-amine (Example 2.138) by replacing Benzyl-(5″-bromo-[2,2′;4′,3″]terpyridin-6′-yl)-amine (Example 1.25) with Benzyl-(5″-bromo-6-methyl-[2,2′;4′,3″]terpyridin-6′-yl)-amine (Example 2.40, step1).

Sources & evidence

ORD record
ord-7c36ae59091b480cab548c14c34271fc
Source dataset
uspto-grants-2013_01
Patent number
US08343966B2

Reaction notes

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