HRID1798831

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21278621

2,5-Dichloro-4-methylpyrimidine

C5H4Cl2N2

结构：CC(C)(C)OC(=O)N1CCC([C@@H]2C[C@@H]2CCO)CC1

HCID66935269

未命名化合物

PRODUCTS

生成物

结构：Cc1nc(N2CCC([C@H]3C[C@H]3CCO)CC2)ncc1Cl

HCID66935254

rel-(1R,2S)-2-[1-(5-Chloro-4-methyl-2-pyrimidinyl)-4-piperidinyl]cyclopropaneethanol

C15H22ClN3O

PROCEDURE

实验过程

The titled compound was prepared from 2,5-dichloro-4-methylpyrimidine from step 1 of this example and rac cis-tert-Butyl 4-[-2-(2-hydroxyethyl)cyclopropyl]piperidine-1-carboxylate by a procedure analogous to Example 6, step 2.