HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 59543416, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 59543444 | HCID 59543444 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59543416 | HCID 59543416 | 80.1% |
Reaction Steps
2″-Methyl-3,4,5,6-tetrahydro-2H-[4,2′;5′,4″]terpyridine-1-carboxylic acid tert-butyl ester (0.54 g, 1.528 mmol) was dissolved in DCM (12 mL), TFA (4mL) was added the reaction mixture was stirred at RT for 2 hours. The reaction mixture was added water and 1N NaOH until pH=12. The organic phase was washed dried with Na2CO3 filtered and evaporation gave 310 mg (80%) yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344001B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-0c77959440574a259d2b5b80deaa0434 |
| Source note | uspto-grants-2013_01 |