Trifluoroacetic acid → HCID 59543408, compound

Participants

Reaction Steps

5-(4-Ethanesulfonylphenyl)-3′,4′,5′,6′-tetrahydro-2′H-[2,4′]bipyridinyl-1′-carboxylic acid tert-butyl ester (0.76 g, 1.675 mmol) was dissolved in DCM (12 mL) and TFA (4 mL) was added. The reaction mixture was stirred for 4 hours. 1N NaOH (20 mL) was added and the DCM phase was washed and dried with Na2CO3, filtered and evaporation gave 462 mg (79%) white crystalline compound.

Provenance & Evidence