Ammonia → HCID 67427904, compound

Participants

Reaction Conditions

Reaction Steps

This compound was prepared by adding triethylamine (66.44 mg, 0.657 mmol) to the stirred solution of Step 1 product (200 mg, 0.43 mmol) in dry THF (5 ml) under nitrogen atmosphere. Ethyl chloroformate (71.40 mg, 0.657 mmol) was added to the reaction mixture which was cooled to −10° C., after a time interval of 30 minutes aqueous ammonia (2 ml, 25%) was added and the reaction mixture was stirred for 30 minutes. Reaction mixture was quenched with water to get off-white solid which was filtered, washed with diethylether and dried under vaccum to get 131 mg of yellow solid.

Provenance & Evidence