Stannous Chloride → HCID 66725103, compound

Participants

Reaction Steps

To a solution of (4R)-4-(4-chloro-2-nitrophenyl)pyrrolidin-2-one (150 mg, 0.714 mmol) in diethyl ether (1 mL) was slowly added a solution of SnCl2 (2 g, 3.21 mmol) in 2 mL of conc. hydrochloric acid. The reaction was vigorous. The reaction mixture was cooled to room temperature and a portion of ice/water was poured onto the reaction mixture. After a few minutes, the mixture was filtered. The solid was collected and washed with cold water to afford the title compound (170 mg, 90% yield). MS (ESI) m/z 211.06 (M+H)+.

Provenance & Evidence