Nitromethane → HCID 73195637, compound

Participants

Reaction Steps

A solution of 4-chloro-3-nitro-benzaldehyde (5 g) and ammonium acetate (3.5 g) in nitromethane (4.5 mL) and acetic acid (20 mL) was heated to reflux for 3 hr, and then cooled to room temperature in an ice bath. The product precipitated as a dark solid. The dark solid was washed with water then ether/hexane (1:1) and dried overnight under vacuum to give 3.5 g of the title compound (75a) as a bright-red solid.

Provenance & Evidence