Nitromethane → HCID 66724814, compound

Participants

Reaction Steps

4-Chloro-3-(phenylmethoxy)benzaldehyde (82d) (1.9 g, 7.7 mmol) was dissolved in 12 mL of acetic acid. To this was added 1.7 g of ammonium acetate and 2.5 mL of nitromethane. The reaction mixture was refluxed for 3 hours. The solution was cooled to room temperature and poured into ice. A green-yellow solid precipitated. The precipitate was filtered, washed with water, and hexane, and vacuum dried to give the 1.6 g (72% yield) of the title compound (82e).

Provenance & Evidence