HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylparaben → N-[4-(Cyclobutylmethoxy)benzoyl]glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | Cyclobutylcarbinol | HCID 78130 | — |
| Reactant | N-[4-(2-Cyclopropylethoxy)benzoyl]glycine | HCID 66812105 | — |
| Product | N-[4-(Cyclobutylmethoxy)benzoyl]glycine | HCID 66812262 | 97% |
Reaction Steps
Reactions similar to those described in Example 1 (1a) and (1b) were conducted using methyl 4-hydroxybenzoate (3.81 g, 25.0 mmol) and cyclobutylmethanol (2.36 mL, 25.0 mmol) to give 6.41 g of the title compound (white powder, yield: 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344029B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-ebc9c3e73fc547c98440695ea6121c24 |
| Source note | uspto-grants-2013_01 |