Ethanolamine → 4-[(2,2-Difluorocyclopropyl)methoxy]-n-{2-[(2-hydroxyethyl)amino]-2-oxo-1-[4-(trifluoromethoxy)benzyl]ethyl}benzamide

Participants

Reaction Steps

A reaction similar to that described in Example 32 (32c) was conducted using 2-({4-[(2,2-difluorocyclopropyl)methoxy]benzoyl}amino)-3-[4-(trifluoromethoxy)phenyl]propanoic acid (352 mg, 0.766 mmol) prepared in Example 40 (40c) and 2-aminoethanol (55 μL, 0.919 mmol) to give 243 mg of the title compound (white powder, yield: 63%).

Provenance & Evidence