HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine → n-{4-[4-(Trifluoromethyl)phenoxy]benzoyl}glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine | HCID 750 | — |
| Reactant | 4-(4-(Trifluoromethyl)phenoxy)benzoic acid | HCID 3673481 | — |
| Product | n-{4-[4-(Trifluoromethyl)phenoxy]benzoyl}glycine | HCID 66812564 | 99% |
Reaction Steps
A reaction similar to that described in Example 1 (1b) was conducted using 4-[4-(trifluoromethyl)phenoxy]benzoic acid (compound described in International Publication No. WO 04/14844, 7.06 g, 25.0 mmol) and glycine (1.88 g, 25.0 mmol) to give 8.38 g of the title compound (white powder, yield: 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344029B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-509ebf9b6b8b4dfd84687b7bc7dade7a |
| Source note | uspto-grants-2013_01 |