tert-Butyl (3-aminopropyl)carbamate → tert-butyl 3-[(2-amino-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-4-yl)amino]propylcarbamate

HRID 179939Notes

Reaction equation

HRID 179939 reaction equation
[Cl:13][c:14]1[c:15]2[c:16]([n:17][c:18]([NH2:20])[n:19]1)-[c:21]1[c:22]([cH:26][cH:27][cH:28][cH:29]1)[CH2:23][CH2:24][CH2:25]2.[NH2:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12]>>[NH:1]([CH2:2][CH2:3][CH2:4][NH:5][C:6]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12])[c:14]1[c:15]2[c:16]([n:17][c:18]([NH2:20])[n:19]1)-[c:21]1[c:22]([cH:26][cH:27][cH:28][cH:29]1)[CH2:23][CH2:24][CH2:25]2

Participants

3

Reactant 2

HCID 2735700tert-Butyl (3-aminopropyl)carbamateHCID 866218984-chloro-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-amine

Product 1

HCID 68603502tert-butyl 3-[(2-amino-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-4-yl)amino]propylcarbamate

Sources & evidence

ORD record
ord-4ca29bfdd47b447bb9bcb0b79e05f164
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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