HCID 59516071, compound → HCID 59516125, compound

HRID 1799411Notes

Reaction equation

HRID 1799411 reaction equation
[C:1]([O:5][C:6]([C:8]1[CH:9]=[N:10][N:11]([CH2:14]C2C=CC(C(OC)=O)=CC=2)[C:12]=1[Cl:13])=[O:7])([CH3:4])([CH3:3])[CH3:2].C(OC(C1C=NN(C[C:39]2[CH:44]=[CH:43][CH:42]=[C:41]([C:45]([O:47][CH3:48])=[O:46])[CH:40]=2)C=1N)=O)(C)(C)C>>[C:1]([O:5][C:6]([C:8]1[CH:9]=[N:10][N:11]([CH2:14][C:39]2[CH:44]=[CH:43][CH:42]=[C:41]([C:45]([O:47][CH3:48])=[O:46])[CH:40]=2)[C:12]=1[Cl:13])=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 59516071HCID 59516071, compoundHCID 59516133HCID 59516133, compound2×

Product 1

HCID 59516125HCID 59516125, compound

Procedure

Compound prepared in an analogous manner to Intermediate #48, replacing 5-Amino-1-(4-methoxycarbonyl-benzyl)-1H-pyrazole-4-carboxylic acid tert-butyl ester with 5-Amino-1-(3-methoxycarbonyl-benzyl)-1H-pyrazole-4-carboxylic acid tert-butyl ester (Intermediate #51)

Sources & evidence

ORD record
ord-d69fcc162e5a47189f85f3ff7de9a0a6
Source dataset
uspto-grants-2013_01
Patent number
US08344016B2

Reaction notes

Loading…