Methyl 1-methylcyclopropyl ketone → N-(2-adamantyl)-3-(1-methylcyclopropyl)-3-oxo-propanamide

HRID 1799417Notes

Reaction equation

HRID 1799417 reaction equation
CC1(C(=O)C)CC1.[CH:8]12[CH2:17][CH:12]3[CH2:13][CH:14]([CH2:16][CH:10]([CH2:11]3)[CH:9]1[NH:18][C:19](=[O:27])[CH2:20][C:21](=[O:26])[C:22]([CH3:25])([CH3:24])[CH3:23])[CH2:15]2>>[CH:8]12[CH2:15][CH:14]3[CH2:13][CH:12]([CH2:11][CH:10]([CH2:16]3)[CH:9]1[NH:18][C:19](=[O:27])[CH2:20][C:21]([C:22]1([CH3:23])[CH2:24][CH2:25]1)=[O:26])[CH2:17]2

Participants

3

Reactant 2

HCID 74067Methyl 1-methylcyclopropyl ketoneHCID 57437904N-(2-adamantyl)-4,4-dimethyl-3-oxo-pentanamide

Product 1

HCID 59516126N-(2-adamantyl)-3-(1-methylcyclopropyl)-3-oxo-propanamide

Procedure

Prepared from 1-(1-methylcyclopropyl)ethanone by the same process as used for Intermediate #60

Sources & evidence

ORD record
ord-5d2965f27497475aa2f946c565b49e98
Source dataset
uspto-grants-2013_01
Patent number
US08344016B2

Reaction notes

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