HCID 59516080, compound → N-(2-adamantyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]-5-tert-butyl-pyrazole-4-carboxamide

HRID 1799433Notes

Reaction equation

HRID 1799433 reaction equation
[C:1]([C:5]1[N:9]([C:10]2[CH:15]=[CH:14][C:13]([Cl:16])=[C:12]([C:17]([F:20])([F:19])[F:18])[CH:11]=2)[N:8]=[CH:7][C:6]=1[C:21]([OH:23])=O)([CH3:4])([CH3:3])[CH3:2].[CH:24]12[CH2:33][CH:28]3[CH2:29][CH:30]([CH2:32][CH:26]([CH2:27]3)[CH:25]1[NH:34]C(C1C=NN(C3C=CC(Cl)=CC=3C)C=1C(C)(C)C)=O)[CH2:31]2>>[CH:24]12[CH2:33][CH:28]3[CH2:29][CH:30]([CH2:32][CH:26]([CH2:27]3)[CH:25]1[NH:34][C:21]([C:6]1[CH:7]=[N:8][N:9]([C:10]3[CH:15]=[CH:14][C:13]([Cl:16])=[C:12]([C:17]([F:18])([F:20])[F:19])[CH:11]=3)[C:5]=1[C:1]([CH3:4])([CH3:3])[CH3:2])=[O:23])[CH2:31]2

Participants

3

Reactant 2

HCID 59516080HCID 59516080, compound2×HCID 59516130N-(2-adamantyl)-1-(4-chloro-2-methyl-phenyl)-5-tert-butyl-pyrazole-4-carboxamide

Product 1

HCID 59516137N-(2-adamantyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]-5-tert-butyl-pyrazole-4-carboxamide

Procedure

N-(2-adamantyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]-5-tert-butyl-pyrazole-4-carboxamide was prepared from 5-tert-butyl-1-(4-chloro-3-(trifluoromethyl)phenyl)-1H-pyrazole-4-carboxylic acid (Intermediate #119) by the same process used for Intermediate #114.

Sources & evidence

ORD record
ord-eb1be37136fa4f7cbfb38a5445be5154
Source dataset
uspto-grants-2013_01
Patent number
US08344016B2

Reaction notes

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