2-Chloro-6-oxetan-3-yl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-[(6-oxetan-3-yl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)amino]thiophene-3-carboxamide

Participants

Reaction Steps

The title compound was prepared according to the general procedure in Example 1 Step 5 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (55 mg, 0.176 mmol) and 2-chloro-6-oxetan-3-yl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one (39.6 mg, 0.176 mmol) as the starting materials.

Provenance & Evidence